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AQUILEA ARTICULAÇÕES FORTE in tablets is a food supplement based on bioactive collagen type II, Boswellia, Curcuma, Hyaluronic acid and vitamin C:
Aquileia contains a complete formula with essential ingredients: Its active ingredients have the following functions:
- Bioactive collagen type II, a protein that is found naturally in cartilage, bones and skin. Proteins, like collagen, contribute to the maintenance of bones and muscles under normal conditions. Type II bioactive collagen has the same structure as collagen found in joints and in the connective tissue of cartilage. Bioactive collagen type ii is a native form of collagen found in the body. It acts on the immune system, to prevent it from attacking the collagen formation itself and thus helps to stop the degradation.
- Curcuma helps to maintain flexibility and well-being in the joints, as well as good mobility. Turmeric has anti-inflammatory properties, helps maintain joint flexibility and well-being, as well as good mobility.
- Boswellia contributes to the comfort and well-being of the joints. Boswellia has anti-inflammatory, calming and analgesic properties, contributes to the comfort and well-being of the joints. [the combination of boswellia with turmeric, improves the action of both plants.]
- Hyaluronic Acid is an essential component that is found naturally in joints and cartilage. Hyaluronic acid - seeks to restore the lubricating, chondroprotective and anti-inflammatory properties of synovial fluid. Promotes cartilage regeneration.
- Vitamin C contributes to the normal formation of collagen for the normal functioning of cartilage, bones and skin. Vitamin C contributes to the normal formation of collagen for the normal functioning of cartilage, bones and skin.
- Black pepper extract - improves bioavailability and helps the action of other active ingredients, such as turmeric and boswellia
Possology: Take 1 tablet daily.
Therapeutic indications of Aquilea forte + joints (tablets):
• anti-inflammatory action
• contributes to joint flexibility
• fights (morning) stiffness one tablet a day, which provides the necessary nutrients for joints:
✓ Who suffers from joint pain
✓ Who feels morning stiffness
✓ Who has loss of mobility and joint flexibility
The use of dietary supplements has been gaining more and more importance these days, and currently more than half of the world population has already consumed dietary supplements at least once in their lives. Food supplements should, however, only be used for the purpose of maintaining, supporting and optimizing the body's normal physiological processes, maintaining homeostasis. The control of weight and muscle mass is considered a fundamental aspect in today's society, involving the consumption of various supplements of vegetable origin. These supplements have several active compounds, making it necessary to know the composition and verify its activity and safety in order to be able to support its use by the population in a conscious way. It is important to be aware of possible interactions with medications or other dietary supplements in the various contexts of application. The production of supplements of vegetable origin must obey a standardization of active compounds and an effective quality control to avoid possible risks. Food supplements of plant origin act in the body by several mechanisms of action, depending on their main active compounds. For weight and muscle mass control, the most used supplements are carbohydrate absorption blockers, metabolism stimulants, body composition modifiers, appetite suppressants, laxatives and diuretics. Among the most consumed plant-based supplements to achieve the goals of weight loss and muscle mass gain are ephedra, garcinia, senna and green tea. Safflower oil, white bean extract, guar gum and dandelion are also supplements of vegetable origin taken for the same purposes.
Food supplements are foodstuffs that are intended to complement the normal diet, providing a concentrated source of nutrients and other substances with a physiological effect. They are marketed in a dosage form and cannot claim properties for the prevention, treatment or cure of diseases (INFARMED, 2016). The use of dietary supplements has been gaining more and more importance in the daily lives of the population. Bearing in mind that a large part of these supplements are of vegetable origin, it is necessary to study and know their composition and activity in order to support their use by the population that consumes them. Currently, food supplements are very widespread and manufacturers resort to medicinal plants and their beneficial characteristics recognized since antiquity and which have been used for the benefit of human health (Costa et al., 2012). Food supplements must be consumed in order to maintain, support or optimize normal physiological processes, that is, maintain the body's homeostasis, without altering or blocking any of these functions. Homeostasis is defined as the status of a person in which the parameters of their biological functions are within the limits considered normal (INFARMED, 2016). Many people use food supplements to control weight and muscle mass to achieve these goals more quickly. The best way to lose or control weight is through the implementation of a healthy diet, with calorie control, along with the practice of sport. The adoption of these guidelines can, however, be complicated for some people who want to achieve goals more quickly. (NIH, 2016).
Legislation / regulation
Food supplements are regulated by the Directorate-General for Food and Veterinary (DGAV), through DL 296/2007, transposed from Directive 2006/374 / EC of the European Commission, of 28 June. Food supplements are defined as foodstuffs whose purpose is to complement the daily diet, as they are concentrated sources of nutrient substances or with nutritional and physiological effect, which are marketed in a dosage form. The forms of commercialization can be capsules, lozenges, tablets, ampoules of liquid, powder sachets, bottles with droppers and other forms similar to liquids or powders that are intended to be taken in small quantities (DL 118/2015). Food supplements can contain a wide variety of compounds, namely vitamins, minerals, isolated or grouped amino acids, essential fatty acids, fibers and various plants and herbal extracts (DL 136/2003). It is not permitted to attribute healing properties to food supplements or associate health claims with them. This function is based only on medicines, as previously defined, and the reference or suggestion of these properties on the supplement labels and advertisements is prohibited (DL 118/2015). Food supplements are subject to the rules established in the legislation applicable to foodstuffs with regard to nutrition and health claims. Additionally, because they are considered foodstuffs, food supplements are not subject to an evaluation or presentation of studies of efficacy, safety and quality before their introduction on the market (CE, 2012b; INFARMED, 2016).
According to DL118 / 2011, the placing on the market of a food supplement only requires the knowledge of the competent authority for that marketing, DGAV, by sending a model of the product in question from the manufacturer or person in charge, not being necessary any other requirements. This label must contain the description of the categories of substances that characterize the product or a specific reference to its nature, the recommended daily intake of the product, the warning that the recommended daily intake should not be exceeded, the indication that food supplements should not be exceeded. be used as substitutes for a varied diet and the warning that products should be kept out of the reach of children. Food law does not prevent substances with pharmacological activity from being incorporated as constituents in food supplements, which means that it is possible to find products on the market containing the same raw material but which are produced and marketed according to different requirements, defined by different organisms and with different rules. This circumstance can generate difficulties in framing a product as a food supplement or as a medicine, being described as border products or “borderline” (INFARMED, 2016). Although the pharmaceutical forms are similar, there are many differences between medications and dietary supplements. The legislation applicable to food supplements is regulated by the European Food Safety Authority (EFSA) and the legislation applicable to medicines, including herbal medicines and homeopathic medicines, is governed by the European Medicines Agency (EMEA). expressed in the Medicines Statute (2006). Under Decree-Law No. 180/2000, the Agency for Quality and Safety (AQSA) was created, which in collaboration with EFSA was initially appointed as the competent authority in Portugal for the assessment of foodstuff risks. In 2004 and according to DL 217-B / 2004, AQSA was replaced by the Portuguese Food Safety Agency, named then as the national entity responsible for assessing and communicating risks in the food chain and having a privileged link with EFSA .
With DL 237/2005, the Food and Economic Security Authority (ASAE) is created, an entity resulting from the merger of several previously existing bodies and where the supervisory functions of the deprived entities have been integrated. This merger aimed to unify the different organizations, in order to improve the performance in the assessment and communication of food risks, as well as the inspection of the activity of economic agents and increasing the efficiency and effectiveness of the performance and improving the articulation with EFSA. According to DL 176/2006, the drug is defined as being any substance or association of substances presented as having curative or preventive properties of diseases in humans or their symptoms or that can be used or administered in humans with a view to establish a medical diagnosis or, exerting a pharmacological, immunological or metabolic action, to restore, correct or modify physiological functions. Herbal medicines are all medicines that have exclusively one or more herbal substances as active substances, one or more herbal preparations or one or more herbal substances in combination with one or more herbal preparations. plants (Medicines Statute, 2006). A homeopathic medicine is described as one that is obtained from substances called homeopathic raw materials, according to a manufacturing process described in the European pharmacopoeia or, failing that, in pharmacopoeia used officially in a member state, and that it can contain several principles (Statute of the Medicament, 2006). The classification of substances as medicines or dietary supplements is not the same in all countries. There is a possibility, even within the EU, that a product could be marketed as a medicine in one country and as a food supplement in another. It appears that, similarly to what happens in Portugal, in most countries the authority that regulates the market for food supplements is not the same as that regulating medicines (INFARMED, 2016). The existence of different concepts, rules and laws in the different EU countries and the need to guarantee food security between Member States has led to the creation of an independent regulatory body, established by Regulation (EC) No. 178/2002, called the Authority European Food Safety Agency (EFSA). Council Directive 79/112 / EC subsequently emerged in an attempt to harmonize the rules on the labeling of foodstuffs. Several changes have been introduced which resulted in the most recent Regulation (EU) No. 1169/2011 of the European Parliament and of the Council. In order to harmonize information on the substances and plant extracts that make up food supplements, the European Commission has been compiling a list of the various substances and their classification as a food supplement, medicine or new food, with the collaboration of several Member States. This characterization has become essential, taking into account that the existing European legislation refers exclusively to vitamins and minerals (EC, 2012a). The EU's situation with regard to legislation and control of food supplements is not unique in the world. Also in the USA, the Food and Drug Administration (FDA) does not require a rigorous analysis of dietary supplements before their implementation on the market. Like the EU, it requires the information on the label that the product in question is not intended to treat, cure or prevent any disease and the composition in terms of ingredients (FDA, 2008).
Based on: SUPERIOR HEALTH SCIENCES INSTITUTE EGAS MONIZ - MASTERS INTEGRATED IN PHARMACEUTICAL SCIENCES - EFFECTIVENESS AND SAFETY OF PLANT SUPPLEMENTS IN WEIGHT CONTROL AND MUSCLE MASS - Work submitted by Marina Isabel Gouveia da Costa Abrantes
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